01 · THE CHALLENGE
Cancer diagnostics must scale with precision oncology
Histopathology remains a cornerstone of modern medicine. However, demands for deeper insights, greater consistency, shorter turnaround times and, where appropriate, seamless integration of molecular diagnostics continue to grow. Conventional methods consume tissue, potentially limiting subsequent diagnostic and molecular analyses.
01
Growing diagnostic demands
Precision medicine requires a holistic view of tissue architecture, spatial information and molecular analysis.
02
Complex
lab realities
High caseloads, numerous process steps and limited personnel define everyday life in diagnostic labs.
03
Fragmented data limits clinical impact
As diagnostic data becomes more complex, disconnected workflows hinder timely treatment decisions.
02 · THE JOURNEY
Every diagnosis begins with a piece of tissue.
Every tissue sample holds valuable information that drives clinical decisions. LIMAA preserves the connection between tissue, imaging data, and diagnostic insights – ensuring full traceability throughout the diagnostic journey.
The intact biopsy
01.
Tissue
Native volumetric data,
ready for diagnostics
02.
Information
Precise diagnosis as part of precision oncology
03.
Decision
03 · THE SHIFT
Digital pathology starts with the tissue – not with a glass slide.
Digitized pathology
PROCESS
Many manual steps: cutting, mounting, scanning
IMAGE TYPE
Scans of selected thin 2D sections on glass slides
CONSISTENCY
Variable – depends on manual handling
TISSUE
Largely consumed during preparation
LIMAA solution
PROCESS
Fully automated workflow from sample to diagnosis
IMAGE TYPE
Native digital tissue images with highest image quality
CONSISTENCY
Standardized, consistent and ready for AI analysis
TISSUE
Preserved tissue samples ready for multi-omics analysis
04 · THE SOLUTION
The complete diagnostic chain.
Native digital histology from a single source – reagents, hardware and software designed as one integrated workflow.
04 · THE SOLUTION
The complete diagnostic chain.
Native digital histology from a single source – reagents, hardware and software designed as one integrated workflow.
Tissue-preserving staining / preparation
(LIMAAstain, LIMAAbodies)
01.
PROPRIETARY REAGENTS
Processing + high-resolution
3D imaging
02.
AUTOMATED HARDWARE
LIMS integration + AI-ready + digital reporting
03.
INTELLIGENT SOFTWARE
EXECUTIVE OVERVIEW · 6 MIN
Pathology, beyond the slide.
05 · THE IMPACT
From biopsy to diagnosis in under 15 min per sample.
120
samples per batch
processed in parallel – 5 bundles of 24
≈ 6 h
hands-on
per batch (120 samples) – the only manual steps
≈ ¾ FTE
staff time
for sample preparation, then automation takes over
≈ 15 min
per sample
per sample from biopsy to diagnosis
VOICES FROM PATHOLOGY
“As a pathologist, I have always struggled with the limitations of traditional histopathology methods, especially the manual processes that often result in tissue loss and longer turnaround times. Integrating LIMAA's fully automated, tissue-preserving histopathology solution into our workflow will transform it remarkably. Overall, LIMAA's innovative technology is not just a step forward; it's a leap into the future of histopathology.”
Prof. Dr. Bruno Märkl
Director of the Institute of Pathology and Molecular Diagnostics, University Hospital Augsburg
VOICES FROM PATHOLOGY
“Thanks to our sample preparation methods and advanced light-sheet microscopy, we can visualize entire tissue samples in 3D without physically sectioning them. Our ability to perform rapid optical sectioning and obtain thousands of digital images in seconds or minutes has significantly increased our throughput.”
Dr. Dr. René Hägerling
Co-Founder of LIMAA Technologies